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Pulmicort


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PULMICORT TURBUHALER is an inhalation-driven, dry powder inhaler designed specifically to eliminate the need for propellants, carriers and other additives. PULMICORT TURBUHALER possesses a multidose system that is preloaded, easily handled and does not require coordinated movements between actuation and inhalation.
Within the TURBUHALER unit is a drug storage compartment containing sufficient drug for 200 metered doses. With TURBUHALER held in an upright position, the patient twists the brown grip fully in one direction and then back again, filling the precisely machined conical holes of the rotating dosing disk with drug. Scrapers remove surplus drug, ensuring accurate dosing.

After the dose has been loaded, the patient exhales away from TURBUHALER, places the mouthpiece between the lips, and inhales forcefully and deeply through the mouth. A patient's inhalation draws air through the cluster of holes in the dosing disk, lifting the dose of budesonide powder through the inhalation channel. This channel leads into a deaggregation zone (a system of two spiral-shaped channels in the mouthpiece) that is aerodynamically designed to create a turbulent flow (hence TURBUHALER). This turbulence causes the budesonide particles in the drug/air mixture to deaggregate to respirable size (<5 micrometers).

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