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Valsartan


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Diovan(Valsartan) Capsules are used to treat Hypertension(High Blood Pressure). Angiotensin II is formed from Angiotensin I from a reaction caused by Angiotensin-converting enzyme(ACE, Kinase II). Angiotensin II is a vascoconstrictor which stimulates the release of aldosterone and the renal reabsorbtion of sodium. Diovan blocks the vasoconstricting effects of Angiotensin II while blocking the release of aldosterone secretions. The blocking of the renin-angiotensin system with ACE Inhibitors is widely used in the treatment of hypertension. Diovan does not inhibit ACE.

Angiotensin is a hormone that causes blood vessels to constrict which results in high blood pressure and puts a strain on the heart. Angiotensin blockers prevent angiotensin from binding to its receptors in the blood vessel walls. This results in lower blood pressure.

Diovan peaks within two to four hours after it is taken. Diovan can be used with diuretics to assist in the lowering of blood pressure also.

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