Sumatriptan
Buy Sumatriptan online
Sumatriptan, which belongs to a group of drugs called triptans (also known as 5-HT1 receptor agonists), is primarily used for treatment of migraine.
Migraine symptoms may be caused by a temporary widening of blood vessels in the head. Sumatriptan is considered to reduce the widening of these blood vessels. This helps the headache and other migraine symptoms such as nausea, vomiting, and sensitivity to light and sound disappears.
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Precautions before using Sumatriptan
Do not use Sumatriptan:
- If you are allergic (hypersensitive) to sumatriptan or any of the other ingredients
- If you have heart problems, such as narrowing of blood vessels (ischemic heart disease), chest pain (angina / angina), or have suffered a heart attack
- If you have problems with blood circulation in your legs that cause cramp-like pain when walking (peripheral vascular disease)
- If you have had a stroke (a stroke) or TIA (transient ischemic disorder of the brain)
- If you have high blood pressure. You can use Sumatriptan if you have treated mild hypertension
- If you have severe liver disease
- If you are taking other migraine medications containing ergotamine or substances similar to ergotamine as methysergide or another triptan/5-HT1 receptor agonist (drugs also used to treat migraine)
- If you are being treated with antidepressants by type monoamine oxidase inhibitor (MAOI) or if you have been treated with these medicines in the past two weeks
If any of these apply to you contact your doctor and do not take Sumatriptan.
Take special care with Sumatriptan and discuss with your doctor:
- If you have any additional risk factors
- If you are a heavy user of tobacco or are undergoing nicotine replacement therapy, especially if you are a man over 40 years, or if you are a woman who has been through the menopause.
In very rare cases, serious heart conditions after taking Sumatriptan have occured although no signs of heart disease were evident before, so if any of these risk factors apply to you, it may mean that you have a higher risk of developing heart disease.
Tell your doctor so that your heart function can be checked before taking Sumatriptan and also:
- If you have a history of seizures or if there are other factors that may increase the risk of convulsions, eg brain damage or alcoholism
- If you have any liver or kidney disease
Please note that if you are allergic to antibiotics called sulfonamides you may also be allergic to Sumatriptan. If you know you are allergic to antibiotics, but if you're not sure if it is a sulphonamide talk to your doctor or pharmacist before taking Sumatriptan.
If you use antidepressant drugs called SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin norepinephrine reuptake inhibitors) do tell your doctor or pharmacist before taking Sumatriptan.
If you use Sumatriptan often it's effectiveness may decline and may even make your headaches worse. Tell your doctor if this applies to you in which case he or she may recommend that you stop taking this drug.
If you feel pain or tightness in your chest after you use Sumatriptan, these symptoms may be intense but they usually pass quickly but if they do not disappear quickly, or if they get worse, seek medical help immediately.
Sumatriptan drug interactions
Tell your doctor if you are taking or have recently taken any other drugs. This includes any herbal remedies or non prescription drugs. Some medicines should not be taken with Sumatriptan and others may cause side effects when used concurrently. You must tell your doctor if you are using:
- ergotamine, which is used to treat migraine, or similar medicines such as methysergide. Do not use Sumatriptan concurrently with these medications. You should stop using them at least 24 hours before using Sumatriptan. Do not take any medicines containing ergotamine or substances similar to ergotamine until at least 6 hours after taking Sumatriptan.
- another triptan/5-HT1 receptor agonist (such as naratriptan, rizatriptan, zolmitriptan), also used for the treatment of migraine. Do not use Sumatriptan concurrently with these medications. You should stop using them at least 24 hours before using Sumatriptan. Do not take any other medicine that contains triptan/5-HT1 receptor agonist for at least 24 hours after taking Sumatriptan.
- SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin norepinephrine reuptake inhibitors) used in the treatment of depression. The use of Sumatriptan together with these medicines may cause serotonin syndrome (a combination of symptoms that may include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle twitching, tremors, palpitations and tremors). If you have these symptoms please tell your doctor.
- MAO (monoamine oxidase inhibitors) used in the treatment of depression. Do not use Sumatriptan if you have taken such drugs during the past two weeks.
St. John's Wort (Hypericum perforatum). During concomitant use of Sumatriptan and herbal preparations containing St. John's Wort, side effects may occur more widely.
Pregnancy and lactation
If you are pregnant or could be pregnant, talk to your doctor before taking Sumatriptan. There is only limited information about the safety of Sumatriptan in pregnant women, although there is no evidence of any increased risk of birth defects to date. Your doctor will discuss with you whether you should use Sumatriptan during pregnancy. Also you should not breastfeed your baby during the next 12 hours after you use Sumatriptan. Breast milk pumped out during those 12 hours should not be given to your children but should be discarded.
Driving and using machines
Both migraine symptoms and your medicine may make you drowsy. If you are affected do not drive or operate machinery. You are responsible for assessing whether you are fit to drive or perform other tasks that require alertness. One of the factors that may affect your ability to do these is the use of drugs because of their effects and / or side effects. Description of these effects can be found below but do discuss with your doctor or pharmacist if you are unsure.
How to use Sumatriptan
Sumatriptan should only be used when the migraine attack has begun. Do not use Sumatriptan for attempting to prevent an attack. Always use Sumatriptan as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
Sumatriptan dosage
The usual dose for adults (18 to 65 years) is one tablet of 50 mg. Some people may need 100 mg. A higher dose than 100 mg do not give a better effect. Sumatriptan is not recommended for people younger than 18 years or older than 65 years.
It is best to take Sumatriptan as soon as you feel a migraine attack has started, but you can take Sumatriptan even later during the attack if so adviced by your doctor or pharmacist:
- If symptoms start to come back
- If the first dose has no effect
However, do not take more than 300 mg Sumatriptan for 24 hours. Taking too much Sumatriptan can make you sick. If you take too much medicine, or if for example a child has taken the drug by mistake, contact your doctor, hospital or poison control center to assess the risk.
If you have further questions about this medicine, ask your doctor or pharmacist.
Sumatriptan side effects
Like all medicines, Sumatriptan can cause side effects although not everybody gets them. Some symptoms may be caused by migraine disease itself.
If you encounter allergic reaction, which is very rare, seek immediate medical attention. Signs of allergy include:
- skin rash
- hives (itchy rash)
- wheezing
- swelling of eyelids, face or lips
- unconsciousness
If you have any of these symptoms soon after taking Sumatriptan do not take more of this medicine and contact your doctor immediately.
Frequently reported Sumatriptan side effects (affecting up to 1 in 10 people):
- pain
- heaviness
- pressure or tightness or pain in the chest, throat or other parts of the body
- unusual sensations, including numbness, tingling and warmth or cold
These symptoms may be intense but usually pass quickly but if these effects continue or become severe (especially chest pain) seem immediate medical assistance. In a small number of people, these symptoms are caused by a heart attack.
Other common side effects include:
- Nausea or vomiting. These symptoms may be part of the migraine attack.
- Fatigue or drowsiness
- Dizziness, feeling weak, feeling of warmth and redness (flushing)
- Transient increases
- Shortness of breath
- Muscle aches
Rare Sumatriptan side effects (affecting up to 1 in 10 000 people) may include changes in liver function. If you take a blood test to check liver function, tell the doctor or nurse that you use Sumatriptan. Some have also reported:
- seizures
- tremors
- muscle spasms
- neck stiffness
- visual disturbances
- heart problems, too-slow or fast heart beat (palpitations), changes in heart rhythm, chest pain (angina) or heart attack
- pale, cyanotic and / or pain in fingers, toes, ears, nose or jaw in response to cold or stress (Raynaud's phenomenon)
- lightheadedness (due to hypotension)
- pain in the lower left abdomen and bloody diarrhea (ischemic colitis)
- diarrhoea
- joint pain
- feeling anxious
- excessive sweating
If any Sumatriptan side effect worsen, or if you notice any side effect not listed here, ask your doctor or pharmacist.
Sumatriptan trade names and more information
Sumatriptan is fairly commonly prescribed across the world and thus sold and marketed under many trade names. Some of the best known are Imitrex, Imigran, Micranil, Migraneitor, Suvalan, Glaxotriptan, Sumax, Somatran, Imigrane, Imiject, Suminat, Cinie, Diletan, Amigrenin and Migraval.
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